Involvement of FAN in TNF-induced apoptosis.

Ségui, B

Involvement of FAN in TNF-induced apoptosis. [electronic resource] - The Journal of clinical investigation Jul 2001 - 143-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9738

10.1172/JCI11498 doi


Amino Acid Chloromethyl Ketones--pharmacology
Animals
Antigens, CD--drug effects
Apoptosis--drug effects
Caspases--metabolism
Cell Line, Transformed
Cells, Cultured--drug effects
Ceramides--biosynthesis
Cysteine Proteinase Inhibitors--pharmacology
Daunorubicin--pharmacology
Enzyme Activation--drug effects
Fibroblasts--cytology
Genes, Dominant
Humans
Hydrolysis
Intercellular Adhesion Molecule-1--biosynthesis
Intracellular Signaling Peptides and Proteins
MAP Kinase Signaling System--drug effects
Mice
Mice, Knockout
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Protein Structure, Tertiary
Proteins--genetics
Receptors, Tumor Necrosis Factor--drug effects
Receptors, Tumor Necrosis Factor, Type I
Recombinant Fusion Proteins--physiology
Second Messenger Systems
Sphingomyelin Phosphodiesterase--metabolism
Sphingomyelins--metabolism
Tumor Necrosis Factor-alpha--pharmacology
U937 Cells