Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.

Meyers, M

Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses. [electronic resource] - Cancer research Jul 2001 - 5193-201 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0008-5472


Adaptor Proteins, Signal Transducing
Animals
Antimetabolites, Antineoplastic--pharmacology
Carrier Proteins
Cell Death--drug effects
Colonic Neoplasms--drug therapy
Cyclin B--metabolism
Cyclin B1
DNA Damage
DNA Repair--physiology
Drug Resistance, Neoplasm
Fibroblasts--cytology
Floxuridine--pharmacology
Fluorouracil--pharmacology
G2 Phase--drug effects
Humans
Intracellular Signaling Peptides and Proteins
Mice
Mitosis--drug effects
MutL Protein Homolog 1
Neoplasm Proteins--deficiency
Nuclear Proteins
Proteins--metabolism
Staining and Labeling--methods
Tumor Cells, Cultured
Tumor Suppressor Protein p53--metabolism
GADD45 Proteins