Evidence that inhibition of cathepsin-B contributes to the neuroprotective properties of caspase inhibitor Tyr-Val-Ala-Asp-chloromethyl ketone.

Gray, J

Evidence that inhibition of cathepsin-B contributes to the neuroprotective properties of caspase inhibitor Tyr-Val-Ala-Asp-chloromethyl ketone. [electronic resource] - The Journal of biological chemistry Aug 2001 - 32750-5 p. digital

Publication Type: Journal Article

0021-9258

10.1074/jbc.M103150200 doi


Amino Acid Chloromethyl Ketones--pharmacology
Animals
Astrocytes--cytology
Binding Sites
Caspase Inhibitors
Cathepsin B--metabolism
Cell Death--drug effects
Cell Line
Cell Survival--drug effects
Cells, Cultured
Cerebellum--cytology
Cysteine Proteinase Inhibitors--pharmacology
Glutamic Acid--pharmacology
Hippocampus--cytology
Mice
Neurons--cytology
Neuroprotective Agents
Organ Culture Techniques
Rats