Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice.

Cisternino, S

Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice. [electronic resource] - Pharmaceutical research Feb 2001 - 183-90 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0724-8741

10.1023/a:1011080418027 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--deficiency
Acridines--pharmacology
Animals
Antineoplastic Agents--pharmacokinetics
Biological Transport
Blood-Brain Barrier
Brain--metabolism
Colchicine--pharmacokinetics
Cyclosporins--pharmacology
Doxorubicin--pharmacokinetics
Drug Resistance, Multiple--physiology
Isoquinolines--pharmacology
Male
Mice
Perfusion
Tetrahydroisoquinolines
Time Factors
Verapamil--pharmacology
Vinblastine--pharmacokinetics