MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1.

Ding, X Z

MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1. [electronic resource] - Biochemical and biophysical research communications Mar 2001 - 447-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-291X

10.1006/bbrc.2001.4595 doi


Cell Cycle--drug effects
Cell Division--drug effects
DNA, Neoplasm--biosynthesis
Enzyme Inhibitors--pharmacology
Flavonoids--pharmacology
Humans
Imidazoles--pharmacology
JNK Mitogen-Activated Protein Kinases
MAP Kinase Signaling System
Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors
Mitogen-Activated Protein Kinases--metabolism
Pancreatic Neoplasms--enzymology
Phosphorylation
Pyridines--pharmacology
Tumor Cells, Cultured
p38 Mitogen-Activated Protein Kinases