Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants.

Butt, E

Heat shock protein 27 is a substrate of cGMP-dependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants. [electronic resource] - The Journal of biological chemistry Mar 2001 - 7108-13 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.m009234200 doi


Actins--metabolism
Binding Sites
Blood Platelets--metabolism
Blotting, Western
Cyclic GMP--analogs & derivatives
Cyclic GMP-Dependent Protein Kinases--chemistry
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
HSP27 Heat-Shock Proteins
Heat-Shock Proteins
Humans
Intracellular Signaling Peptides and Proteins
Mass Spectrometry
Mitogen-Activated Protein Kinases--metabolism
Molecular Chaperones
Mutagenesis, Site-Directed
Neoplasm Proteins--chemistry
Phosphorylation
Platelet Aggregation
Protein Serine-Threonine Kinases--metabolism
Serine--chemistry
Signal Transduction
Spectrometry, Fluorescence
Spectrometry, Mass, Electrospray Ionization
Substrate Specificity
Thionucleotides--pharmacology
Threonine--chemistry
Time Factors
p38 Mitogen-Activated Protein Kinases