Genetic differences in the aromatic hydrocarbon-inducible n-hydroxylation of 2-acetylaminofluorene and acetaminophen-produced hepatotoxicity in mice.

Thorgeirsson, S S

Genetic differences in the aromatic hydrocarbon-inducible n-hydroxylation of 2-acetylaminofluorene and acetaminophen-produced hepatotoxicity in mice. [electronic resource] - Molecular pharmacology Mar 1975 - 159-65 p. digital

Publication Type: Journal Article

0026-895X


2-Acetylaminofluorene--metabolism
Acetaminophen--toxicity
Animals
Chemical and Drug Induced Liver Injury--enzymology
Enzyme Induction--drug effects
Fluorenes--metabolism
Hydrocarbons
In Vitro Techniques
Kinetics
Methylcholanthrene--pharmacology
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Microsomes, Liver--enzymology
Mixed Function Oxygenases--metabolism
Molecular Biology