Up-regulation of cyclin-dependent kinase 4/cyclin D2 expression but down-regulation of cyclin-dependent kinase 2/cyclin E in testicular germ cell tumors.

Schmidt, B A

Up-regulation of cyclin-dependent kinase 4/cyclin D2 expression but down-regulation of cyclin-dependent kinase 2/cyclin E in testicular germ cell tumors. [electronic resource] - Cancer research May 2001 - 4214-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


CDC2-CDC28 Kinases
Cyclin D1--biosynthesis
Cyclin D2
Cyclin E--biosynthesis
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinases--biosynthesis
Cyclins--biosynthesis
Down-Regulation
G1 Phase--physiology
Gene Expression Regulation, Neoplastic
Germinoma--genetics
Humans
Immunohistochemistry
Male
Protein Serine-Threonine Kinases--biosynthesis
Proto-Oncogene Proteins
RNA, Messenger--biosynthesis
Retinoblastoma Protein--physiology
Reverse Transcriptase Polymerase Chain Reaction
S Phase--physiology
Testicular Neoplasms--genetics
Up-Regulation