Low in vivo toxicity of a novel cisplatin-ursodeoxycholic derivative (Bamet-UD2) with enhanced cytostatic activity versus liver tumors.

Dominguez, M F

Low in vivo toxicity of a novel cisplatin-ursodeoxycholic derivative (Bamet-UD2) with enhanced cytostatic activity versus liver tumors. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jun 2001 - 1106-12 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-3565


Animals
Antineoplastic Agents--administration & dosage
Bone Marrow--chemistry
Carcinoma, Hepatocellular--chemistry
Cisplatin--administration & dosage
Disease Models, Animal
Drug Evaluation, Preclinical
Injections, Intraperitoneal
Kidney--chemistry
Kidney Function Tests
Liver--chemistry
Liver Neoplasms, Experimental--chemistry
Male
Mice
Mice, Nude
Myocardium--chemistry
Neoplasm Transplantation
Neural Conduction--drug effects
Organoplatinum Compounds--administration & dosage
Platinum--analysis
Rats
Rats, Wistar
Sciatic Nerve--chemistry
Survival Rate
Tissue Distribution
Tumor Cells, Cultured
Ursodeoxycholic Acid--administration & dosage