Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.

Kagawa, S

Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research May 2001 - 1474-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1078-0432


Apoptosis--physiology
Caspase 3
Caspase 6
Caspases--deficiency
Cell Nucleus--physiology
DNA Fragmentation
Enzyme Activation
Humans
Lamin Type B
Lamins
Nuclear Proteins--metabolism
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-bcl-2
Transfection
Tumor Cells, Cultured
bcl-2-Associated X Protein