Efficient retrovirus-mediated PIG-A gene transfer and stable restoration of GPI-anchored protein expression in cells with the PNH phenotype.
Efficient retrovirus-mediated PIG-A gene transfer and stable restoration of GPI-anchored protein expression in cells with the PNH phenotype. [electronic resource]
- Blood May 2001
- 3004-10 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-4971
10.1182/blood.v97.10.3004 doi
3T3 Cells
Animals
B-Lymphocytes--metabolism
Bone Marrow Cells--metabolism
Cell Line
Cell Line, Transformed
Gene Expression
Genetic Vectors
Glycosylphosphatidylinositols--genetics
Hematopoietic Stem Cells--metabolism
Hemoglobinuria, Paroxysmal--blood
Hemolysis
Herpesvirus 4, Human
Membrane Proteins--deficiency
Mice
Mutation
Nerve Growth Factor--analysis
Phenotype
Retroviridae--genetics
Transfection
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-4971
10.1182/blood.v97.10.3004 doi
3T3 Cells
Animals
B-Lymphocytes--metabolism
Bone Marrow Cells--metabolism
Cell Line
Cell Line, Transformed
Gene Expression
Genetic Vectors
Glycosylphosphatidylinositols--genetics
Hematopoietic Stem Cells--metabolism
Hemoglobinuria, Paroxysmal--blood
Hemolysis
Herpesvirus 4, Human
Membrane Proteins--deficiency
Mice
Mutation
Nerve Growth Factor--analysis
Phenotype
Retroviridae--genetics
Transfection