Vitamin D(3)-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1.

McGuire, T F

Vitamin D(3)-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1. [electronic resource] - The Journal of biological chemistry Jul 2001 - 26365-73 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M010101200 doi


Animals
Apoptosis--drug effects
Carcinoma, Squamous Cell--metabolism
Caspases--metabolism
Cholecalciferol--pharmacology
Humans
MAP Kinase Kinase Kinase 1
Mice
Protein Serine-Threonine Kinases--metabolism
Signal Transduction
Tumor Cells, Cultured
Up-Regulation