A nucleus-localization-deficient mutant serves as a dominant-negative inhibitor of gut-enriched Krüppel-like factor function.

Shie, J L

A nucleus-localization-deficient mutant serves as a dominant-negative inhibitor of gut-enriched Krüppel-like factor function. [electronic resource] - Biochemical and biophysical research communications Apr 2001 - 205-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0006-291X

10.1006/bbrc.2001.4762 doi


Active Transport, Cell Nucleus--physiology
Amino Acid Substitution--genetics
Cell Line
Cyclin D1--genetics
DNA--biosynthesis
DNA-Binding Proteins--genetics
Genes, Dominant--physiology
Genes, Reporter
Green Fluorescent Proteins
HT29 Cells
Humans
Kruppel-Like Factor 4
Kruppel-Like Transcription Factors
Luminescent Proteins--genetics
Mutagenesis, Site-Directed
Nuclear Localization Signals--physiology
Promoter Regions, Genetic--drug effects
Recombinant Fusion Proteins--genetics
Structure-Activity Relationship
Thymidine--metabolism
Transcription Factors--genetics
Transfection