A polymorphism in the 5' untranslated region and a Met229-->Leu variant in exon 5 of the human UCP1 gene are associated with susceptibility to type II diabetes mellitus.

Mori, H

A polymorphism in the 5' untranslated region and a Met229-->Leu variant in exon 5 of the human UCP1 gene are associated with susceptibility to type II diabetes mellitus. [electronic resource] - Diabetologia Mar 2001 - 373-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0012-186X

10.1007/s001250051629 doi


5' Untranslated Regions--genetics
Aged
Alleles
Amino Acid Substitution
Asian People--genetics
Carrier Proteins--genetics
Diabetes Mellitus, Type 2--genetics
Exons
Female
Gene Frequency
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Ion Channels
Japan
Leucine
Male
Membrane Proteins--genetics
Methionine
Middle Aged
Mitochondria--genetics
Mitochondrial Proteins
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Polymorphism, Single-Stranded Conformational
Reference Values
Uncoupling Protein 1