Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors.

Blagosklonny, M V

Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors. [electronic resource] - Oncogene Jan 2001 - 395-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

0950-9232

10.1038/sj.onc.1204055 doi


Animals
DNA-Binding Proteins--genetics
Humans
Hypoxia-Inducible Factor 1
Hypoxia-Inducible Factor 1, alpha Subunit
Ligases
Nuclear Proteins--genetics
Proteins--genetics
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-mdm2
Transcription Factors
Tumor Suppressor Protein p53--genetics
Tumor Suppressor Proteins
Ubiquitin-Protein Ligases
Von Hippel-Lindau Tumor Suppressor Protein