Kinetics study of the biotransformation of an oligonucleotide prodrug in cells extract by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry.

Brès, J C

Kinetics study of the biotransformation of an oligonucleotide prodrug in cells extract by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry. [electronic resource] - Journal of chromatography. B, Biomedical sciences and applications Mar 2001 - 123-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1387-2273

10.1016/s0378-4347(00)00502-8 doi


Biotransformation
Cell Extracts
Oligonucleotides--chemistry
Prodrugs--pharmacokinetics
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Thymidine--chemistry