Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1.

Fortin, J F

Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1. [electronic resource] - Blood Apr 2001 - 2390-400 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood.v97.8.2390 doi


Active Transport, Cell Nucleus
Adult
Cyclosporine--pharmacology
DNA-Binding Proteins--physiology
Enzyme Inhibitors--pharmacology
Gene Expression Regulation--drug effects
HIV Long Terminal Repeat--physiology
HIV-1--physiology
Humans
Immunosuppressive Agents--pharmacology
Interleukin-1--genetics
Interleukin-2--pharmacology
Intracellular Signaling Peptides and Proteins
Ionomycin--pharmacology
Jurkat Cells--drug effects
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)--deficiency
NF-kappa B--physiology
NFATC Transcription Factors
Nuclear Proteins
Organometallic Compounds--pharmacology
Phytohemagglutinins--pharmacology
Promoter Regions, Genetic--drug effects
Protein Transport
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases--antagonists & inhibitors
Protein-Tyrosine Kinases--physiology
Receptors, Antigen, T-Cell--physiology
Recombinant Fusion Proteins--biosynthesis
Recombinant Proteins--pharmacology
Tacrolimus--pharmacology
Tetradecanoylphorbol Acetate--pharmacology
Transcription Factors--physiology
Transcription, Genetic--drug effects
ZAP-70 Protein-Tyrosine Kinase