Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions.

Murphy, L O

Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions. [electronic resource] - British journal of cancer Apr 2001 - 926-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0007-0920

10.1054/bjoc.2001.1698 doi


Cell Division--physiology
Culture Media, Serum-Free
Enzyme Activation
Enzyme Inhibitors--pharmacology
Epidermal Growth Factor--metabolism
ErbB Receptors--metabolism
Flavonoids--pharmacology
Gastrin-Releasing Peptide--metabolism
Gene Expression Regulation, Neoplastic
Humans
Insulin-Like Growth Factor I--metabolism
MAP Kinase Signaling System--physiology
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--antagonists & inhibitors
Pancreatic Neoplasms--metabolism
Quinazolines
Substrate Specificity
Transcription Factor AP-1--biosynthesis
Tumor Cells, Cultured
Tyrphostins--pharmacology