Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.

Kuriyama, N

Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model. [electronic resource] - Cancer research Mar 2001 - 1805-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


Adenoviridae--genetics
Animals
Brain Neoplasms--metabolism
Collagenases--metabolism
Endopeptidases--metabolism
Extracellular Matrix Proteins--metabolism
Female
Ganciclovir--pharmacology
Genetic Therapy--methods
Genetic Vectors--genetics
Glioblastoma--metabolism
Humans
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Metastasis
Rats
Rats, Inbred F344
Simplexvirus--enzymology
Thymidine Kinase--genetics
Trypsin--metabolism
Tumor Cells, Cultured
Xenograft Model Antitumor Assays