Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors.
Podust, L M
Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 2001 - 3068-73 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.061562898 doi
Amino Acid Sequence
Antifungal Agents--chemistry
Candida albicans--drug effects
Crystallography, X-Ray
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--chemistry
Drug Resistance, Microbial
Enzyme Inhibitors--chemistry
Fluconazole--chemistry
Imidazoles--chemistry
Molecular Sequence Data
Mycobacterium tuberculosis--enzymology
Oxidoreductases--antagonists & inhibitors
Peptide Mapping
Protein Structure, Tertiary
Sterol 14-Demethylase
Substrate Specificity
Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 2001 - 3068-73 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.061562898 doi
Amino Acid Sequence
Antifungal Agents--chemistry
Candida albicans--drug effects
Crystallography, X-Ray
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--chemistry
Drug Resistance, Microbial
Enzyme Inhibitors--chemistry
Fluconazole--chemistry
Imidazoles--chemistry
Molecular Sequence Data
Mycobacterium tuberculosis--enzymology
Oxidoreductases--antagonists & inhibitors
Peptide Mapping
Protein Structure, Tertiary
Sterol 14-Demethylase
Substrate Specificity