Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen.

Shah, A A

Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen. [electronic resource] - Gut Mar 2001 - 339-46 p. digital

Publication Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

0017-5749

10.1136/gut.48.3.339 doi


Adolescent
Adult
Aged
Biomarkers
Cross-Over Studies
Cyclooxygenase Inhibitors--adverse effects
Double-Blind Method
Female
Gastric Mucosa--drug effects
Gastrointestinal Diseases--chemically induced
Humans
Intestinal Mucosa--drug effects
Male
Middle Aged
Naproxen--adverse effects
Permeability--drug effects
Platelet Aggregation--drug effects
Prostaglandins E--metabolism
Sulfonamides--adverse effects
Thromboxane B2--blood