Preliminary studies on the effect of dehydroepiandrosterone (DHEA) on both constitutive and phytohaemagglutinin (PHA)-inducible IL-6 and IL-2 mRNA expression and cytokine production in human spleen mononuclear cell suspensions in vitro.

Young, D G

Preliminary studies on the effect of dehydroepiandrosterone (DHEA) on both constitutive and phytohaemagglutinin (PHA)-inducible IL-6 and IL-2 mRNA expression and cytokine production in human spleen mononuclear cell suspensions in vitro. [electronic resource] - Clinical and experimental immunology Jan 2001 - 28-35 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-9104

10.1046/j.1365-2249.2001.01445.x doi


Adjuvants, Immunologic--pharmacology
Adolescent
Adult
Aged
Cells, Cultured
Cyclosporins--pharmacology
Cytokines--antagonists & inhibitors
Dehydroepiandrosterone--pharmacology
Dexamethasone--pharmacology
Dose-Response Relationship, Immunologic
Female
Humans
Immunosuppressive Agents--pharmacology
Interleukin-2--antagonists & inhibitors
Interleukin-6--antagonists & inhibitors
Leukocytes, Mononuclear--drug effects
Male
Middle Aged
Phytohemagglutinins--antagonists & inhibitors
RNA, Messenger--antagonists & inhibitors
Spleen--cytology