beta1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway.

Bonfoco, E

beta1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway. [electronic resource] - Neuroscience 2000 - 1145-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0306-4522

10.1016/s0306-4522(00)00429-2 doi


Antibodies, Monoclonal--pharmacology
Apoptosis
Carrier Proteins--metabolism
Caspase 3
Caspase 9
Caspases--metabolism
Cell Adhesion
Cell Differentiation
Cytochrome c Group--metabolism
Enzyme Activation
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Humans
Integrin beta1--immunology
Neuroblastoma--pathology
Phosphorylation--drug effects
Protein Serine-Threonine Kinases
Protein-Tyrosine Kinases--chemistry
Proto-Oncogene Proteins--antagonists & inhibitors
Proto-Oncogene Proteins c-akt
Signal Transduction
Tumor Cells, Cultured
bcl-Associated Death Protein