Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling.
Sumitomo, M
Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling. [electronic resource] - The Journal of clinical investigation Dec 2000 - 1399-407 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9738
10.1172/JCI10536 doi
Animals
Bombesin--pharmacology
COS Cells
Cell Movement--drug effects
Culture Media, Serum-Free--pharmacology
DNA, Recombinant--genetics
Endothelin-1--pharmacology
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Humans
Male
Membrane Proteins--genetics
Neprilysin--genetics
Organophosphonates--pharmacology
Phenylalanine--analogs & derivatives
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation--drug effects
Protein Binding
Protein-Tyrosine Kinases--metabolism
Proto-Oncogene Proteins pp60(c-src)--metabolism
Signal Transduction
Tumor Cells, Cultured
src-Family Kinases--metabolism
Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling. [electronic resource] - The Journal of clinical investigation Dec 2000 - 1399-407 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9738
10.1172/JCI10536 doi
Animals
Bombesin--pharmacology
COS Cells
Cell Movement--drug effects
Culture Media, Serum-Free--pharmacology
DNA, Recombinant--genetics
Endothelin-1--pharmacology
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
Humans
Male
Membrane Proteins--genetics
Neprilysin--genetics
Organophosphonates--pharmacology
Phenylalanine--analogs & derivatives
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation--drug effects
Protein Binding
Protein-Tyrosine Kinases--metabolism
Proto-Oncogene Proteins pp60(c-src)--metabolism
Signal Transduction
Tumor Cells, Cultured
src-Family Kinases--metabolism