Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents.

Shi, J

Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents. [electronic resource] - Neuron Oct 2000 - 103-14 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0896-6273

10.1016/s0896-6273(00)00089-1 doi


Action Potentials--drug effects
Calcineurin--metabolism
Calcineurin Inhibitors
Dose-Response Relationship, Drug
Down-Regulation--genetics
Electric Stimulation
Enzyme Inhibitors--pharmacology
Excitatory Amino Acid Antagonists--pharmacology
Excitatory Postsynaptic Potentials--physiology
Gene Expression Regulation, Developmental--drug effects
In Vitro Techniques
Ion Transport--drug effects
Neuronal Plasticity--physiology
Neurons--cytology
Patch-Clamp Techniques
Piperidines--pharmacology
Receptors, N-Methyl-D-Aspartate--genetics
Superior Colliculi--cytology
Synapses--metabolism
Tacrolimus--pharmacology