Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells.

Weinstein-Oppenheimer, C

Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells. [electronic resource] - Leukemia Nov 2000 - 1921-38 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0887-6924

10.1038/sj.leu.2401926 doi


Animals
Apoptosis--drug effects
CD11 Antigens--biosynthesis
Cell Aggregation--drug effects
Cell Differentiation--drug effects
Cell Size--drug effects
DNA Replication--drug effects
DNA, Complementary--genetics
Enzyme Activation
Estradiol--pharmacology
Gene Expression Regulation--drug effects
Granulocyte-Macrophage Colony-Stimulating Factor--biosynthesis
Humans
Integrins--biosynthesis
Interleukin-3--pharmacology
Leukemia, Erythroblastic, Acute--pathology
MAP Kinase Kinase Kinases--metabolism
MAP Kinase Signaling System
Mice
Mice, Inbred DBA
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--metabolism
Myeloid Progenitor Cells--drug effects
Neoplasm Proteins--genetics
Phosphorylation--drug effects
Protein Processing, Post-Translational--drug effects
Protein Subunits
Proto-Oncogene Proteins c-raf--genetics
Receptors, Cytokine--biosynthesis
Receptors, Estrogen--genetics
Recombinant Fusion Proteins--genetics
Tamoxifen--analogs & derivatives
Tetradecanoylphorbol Acetate--pharmacology
Transfection
Tretinoin--pharmacology
Tumor Cells, Cultured--drug effects