Inhibition of matrix metalloproteinase activity attenuates tenascin-C production and calcification of implanted purified elastin in rats.

Vyavahare, N

Inhibition of matrix metalloproteinase activity attenuates tenascin-C production and calcification of implanted purified elastin in rats. [electronic resource] - The American journal of pathology Sep 2000 - 885-93 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0002-9440

10.1016/S0002-9440(10)64602-0 doi


Alkaline Phosphatase--metabolism
Animals
Benzyl Compounds
Calcinosis--metabolism
Dexamethasone--pharmacology
Disease Models, Animal
Drug Combinations
Elastin--drug effects
Enzyme Inhibitors--pharmacology
Immunoenzyme Techniques
Implants, Experimental
Male
Matrix Metalloproteinase 2--physiology
Matrix Metalloproteinase 9--physiology
Matrix Metalloproteinase Inhibitors
Pentoxifylline--pharmacology
Protease Inhibitors--pharmacology
Rats
Rats, Sprague-Dawley
Succinates
Tenascin--biosynthesis