CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity.

Shin, S Y

CRAMP analogues having potent antibiotic activity against bacterial, fungal, and tumor cells without hemolytic activity. [electronic resource] - Biochemical and biophysical research communications Sep 2000 - 904-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-291X

10.1006/bbrc.2000.3269 doi


Amino Acid Sequence
Amino Acid Substitution
Anti-Bacterial Agents
Anti-Infective Agents--chemical synthesis
Antifungal Agents--chemical synthesis
Antimicrobial Cationic Peptides
Antineoplastic Agents--chemical synthesis
Bacteria--drug effects
Cathelicidins
Circular Dichroism
Dose-Response Relationship, Drug
Drug Design
Erythrocytes--drug effects
Fungi--drug effects
Hemolysis--drug effects
Humans
Lysine--chemistry
Micelles
Molecular Sequence Data
Peptides--chemical synthesis
Protein Structure, Secondary
Proteins--chemistry
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Structure-Activity Relationship
Tumor Cells, Cultured