Two transport binding sites of P-glycoprotein are unequal yet contingent: initial rate kinetic analysis by ATP hydrolysis demonstrates intersite dependence.

Wang, E J

Two transport binding sites of P-glycoprotein are unequal yet contingent: initial rate kinetic analysis by ATP hydrolysis demonstrates intersite dependence. [electronic resource] - Biochimica et biophysica acta Aug 2000 - 63-74 p. digital

Publication Type: Comparative Study; Journal Article

0006-3002

10.1016/s0167-4838(00)00125-4 doi


ATP Binding Cassette Transporter, Subfamily B--metabolism
ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism
ATP-Binding Cassette Transporters--metabolism
Adenosine Triphosphatases--metabolism
Benzimidazoles--antagonists & inhibitors
Binding Sites
Binding, Competitive
Biological Transport
Cell Membrane--metabolism
Fluorescent Dyes
Kinetics
Onium Compounds
Organophosphorus Compounds
Protein Binding
Substrate Specificity
Tumor Cells, Cultured