Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.

van Aalten, D M

Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes. [electronic resource] - Biochemistry Aug 2000 - 10082-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

0006-2960

10.1021/bi000952h doi


Binding Sites
Carboxypeptidases--antagonists & inhibitors
Carboxypeptidases A
Crystallography
Cysteine--chemistry
Drug Design
Enzyme Inhibitors--chemistry
Metalloproteins--antagonists & inhibitors
Models, Molecular
Motion
Penicillamine--metabolism
Stereoisomerism
Zinc--metabolism