Acidic amino acids flanking phosphorylation sites in the M2 muscarinic receptor regulate receptor phosphorylation, internalization, and interaction with arrestins.

Lee, K B

Acidic amino acids flanking phosphorylation sites in the M2 muscarinic receptor regulate receptor phosphorylation, internalization, and interaction with arrestins. [electronic resource] - The Journal of biological chemistry Nov 2000 - 35767-77 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M002225200 doi


Amino Acid Sequence
Amino Acid Substitution--genetics
Amino Acids--metabolism
Animals
Arrestins--chemistry
Carbachol--metabolism
Cattle
Cell Line
Cholinergic Agonists--metabolism
Endocytosis
Humans
Inhibitory Concentration 50
Molecular Sequence Data
Mutagenesis--genetics
Phosphorylation--drug effects
Precipitin Tests
Protein Binding
Receptor, Muscarinic M2
Receptors, Muscarinic--chemistry
Transfection