Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes.

Wharton, W

Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes. [electronic resource] - The Journal of biological chemistry Oct 2000 - 33981-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M005600200 doi


3T3 Cells
Animals
Cell Cycle
Cell Cycle Proteins
Cell Division--drug effects
Cyclin D1--metabolism
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclin-Dependent Kinases--metabolism
Cyclins--physiology
DNA--metabolism
Enzyme Inhibitors--pharmacology
Gene Expression--drug effects
Histone Deacetylase Inhibitors
Hydroxamic Acids--pharmacology
Mice
Microtubule-Associated Proteins--physiology
Platelet-Derived Growth Factor--pharmacology
Tumor Suppressor Proteins