Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.

Reshetnikova, G

Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein. [electronic resource] - Experimental cell research Aug 2000 - 35-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0014-4827

10.1006/excr.2000.4966 doi


3T3 Cells
Actins--metabolism
Animals
Blood Proteins--pharmacology
Blotting, Western
CDC2-CDC28 Kinases
Cell Cycle Proteins
Cell Nucleus--chemistry
Cyclin D1--analysis
Cyclin E--analysis
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclin-Dependent Kinases--analysis
Cyclins--metabolism
Cytochalasin B--analogs & derivatives
Cytoplasm--chemistry
Cytoskeleton--metabolism
Fluorescent Antibody Technique
G1 Phase--drug effects
Gene Expression Regulation, Enzymologic
Mice
Microtubule-Associated Proteins--metabolism
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--metabolism
Mitogens--pharmacology
Nuclear Proteins--metabolism
Phosphorylation
Protein Serine-Threonine Kinases--analysis
Proto-Oncogene Proteins
RNA, Messenger--analysis
Retinoblastoma Protein--metabolism
Retinoblastoma-Like Protein p107
S Phase--drug effects
Tumor Suppressor Proteins