Synthesis and pharmacological evaluation of cis-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-1-ones. Tricyclic analogues related to the antilipidemic drug clofibrate.
Witiak, D T
Synthesis and pharmacological evaluation of cis-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-1-ones. Tricyclic analogues related to the antilipidemic drug clofibrate. [electronic resource] - Journal of medicinal chemistry Jun 1979 - 699-705 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm00192a017 doi
Animals
Benzofurans--chemical synthesis
Cholesterol--blood
Clofibrate--analogs & derivatives
Ethylmorphine-N-Demethylase--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lactones--chemical synthesis
Liver--drug effects
Magnetic Resonance Spectroscopy
Male
Microsomes, Liver--enzymology
NADPH-Ferrihemoprotein Reductase--metabolism
Rats
Triglycerides--blood
Synthesis and pharmacological evaluation of cis-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-1-ones. Tricyclic analogues related to the antilipidemic drug clofibrate. [electronic resource] - Journal of medicinal chemistry Jun 1979 - 699-705 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm00192a017 doi
Animals
Benzofurans--chemical synthesis
Cholesterol--blood
Clofibrate--analogs & derivatives
Ethylmorphine-N-Demethylase--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lactones--chemical synthesis
Liver--drug effects
Magnetic Resonance Spectroscopy
Male
Microsomes, Liver--enzymology
NADPH-Ferrihemoprotein Reductase--metabolism
Rats
Triglycerides--blood