Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy.

Yamashita, H

Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy. [electronic resource] - The Journal of biological chemistry Sep 2000 - 28045-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M005485200 doi


Actins--metabolism
Amino Acid Sequence
Amino Acid Substitution
Animals
Binding Sites
Cardiomyopathy, Hypertrophic--genetics
Chickens
Conserved Sequence
Crystallography, X-Ray
Gizzard, Avian
Humans
Kinetics
Models, Molecular
Muscle, Smooth--metabolism
Muscle, Smooth, Vascular--metabolism
Mutagenesis, Site-Directed
Myocardium--metabolism
Myosin Heavy Chains--chemistry
Myosins--chemistry
Point Mutation
Protein Conformation
Protein Structure, Secondary