Rapid induction of nuclear transcripts and inhibition of intron decay in response to the polymerase II inhibitor DRB.

Clement, J Q

Rapid induction of nuclear transcripts and inhibition of intron decay in response to the polymerase II inhibitor DRB. [electronic resource] - Journal of molecular biology Jun 2000 - 1179-91 p. digital

Publication Type: Journal Article

0022-2836

10.1006/jmbi.2000.3745 doi


Cell Nucleus--drug effects
Dactinomycin--pharmacology
Dichlororibofuranosylbenzimidazole--pharmacology
Dose-Response Relationship, Drug
Genes--genetics
Genes, T-Cell Receptor beta--genetics
Half-Life
HeLa Cells
Humans
Introns--genetics
Promoter Regions, Genetic--genetics
RNA Polymerase II--antagonists & inhibitors
RNA Precursors--biosynthesis
RNA Processing, Post-Transcriptional--drug effects
RNA Stability--drug effects
RNA, Messenger--biosynthesis
Substrate Specificity
Tetracycline--pharmacology
Time Factors
Transcription, Genetic--drug effects
Transfection
Up-Regulation--drug effects