Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction.

Lode, H N

Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction. [electronic resource] - The Journal of clinical investigation Jun 2000 - 1623-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9738

10.1172/JCI9177 doi


Animals
Antigen-Presenting Cells--physiology
CD4-Positive T-Lymphocytes--immunology
CD40 Antigens--genetics
CD40 Ligand
Female
Interleukin-2--therapeutic use
Lymphocyte Activation
Melanoma, Experimental--immunology
Membrane Glycoproteins--genetics
Mice
Mice, Inbred C57BL
Mice, Knockout