A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.

Smith, C C

A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells. [electronic resource] - The Journal of biological chemistry Aug 2000 - 25690-9 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M002140200 doi


Amino Acid Sequence
Base Sequence
Blotting, Northern
Blotting, Southern
Cell Division
Cell Line
Cloning, Molecular
DNA, Complementary--metabolism
Gene Library
Glutathione Transferase--metabolism
HeLa Cells
Heat-Shock Proteins
Humans
Immunoblotting
Ions
Lysine--metabolism
Manganese--metabolism
Melanoma--metabolism
Molecular Chaperones
Molecular Sequence Data
Oligonucleotides, Antisense--metabolism
Open Reading Frames
Phosphorylation
Plasmids--metabolism
Precipitin Tests
Protein Biosynthesis
Protein Kinases--chemistry
Protein Serine-Threonine Kinases--biosynthesis
Protein Structure, Tertiary
Recombinant Fusion Proteins--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Ribonucleotide Reductases--biosynthesis
Transfection
Tumor Cells, Cultured