A human class II MHC-derived peptide antagonizes phosphatidylinositol 3-kinase to block IL-2 signaling.
Boytim, M L
A human class II MHC-derived peptide antagonizes phosphatidylinositol 3-kinase to block IL-2 signaling. [electronic resource] - The Journal of clinical investigation May 2000 - 1447-53 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9738
10.1172/JCI8139 doi
Amino Acid Sequence
Cell Membrane--metabolism
Cells, Cultured
Histocompatibility Antigens Class II--chemistry
Humans
Interleukin-2--metabolism
Lymphocyte Activation
Models, Biological
Molecular Sequence Data
Peptide Fragments--chemistry
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation
Receptors, Interleukin-2--metabolism
Ribosomal Protein S6 Kinases--antagonists & inhibitors
Signal Transduction
T-Lymphocytes--metabolism
Tyrosine--metabolism
A human class II MHC-derived peptide antagonizes phosphatidylinositol 3-kinase to block IL-2 signaling. [electronic resource] - The Journal of clinical investigation May 2000 - 1447-53 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9738
10.1172/JCI8139 doi
Amino Acid Sequence
Cell Membrane--metabolism
Cells, Cultured
Histocompatibility Antigens Class II--chemistry
Humans
Interleukin-2--metabolism
Lymphocyte Activation
Models, Biological
Molecular Sequence Data
Peptide Fragments--chemistry
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation
Receptors, Interleukin-2--metabolism
Ribosomal Protein S6 Kinases--antagonists & inhibitors
Signal Transduction
T-Lymphocytes--metabolism
Tyrosine--metabolism