Differential regulation of cyclooxygenase-2 (COX-2) mRNA stability by interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) in human in vitro differentiated macrophages.

Huang, Z F

Differential regulation of cyclooxygenase-2 (COX-2) mRNA stability by interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) in human in vitro differentiated macrophages. [electronic resource] - Biochemical pharmacology Jan 2000 - 187-94 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-2952

10.1016/s0006-2952(99)00312-3 doi


Cell Differentiation
Cyclooxygenase 2
Drug Synergism
Gene Expression Regulation, Enzymologic
Humans
In Vitro Techniques
Interleukin-1--pharmacology
Isoenzymes--genetics
Lipopolysaccharides--pharmacology
Macrophages--drug effects
Membrane Proteins
Prostaglandin-Endoperoxide Synthases--genetics
RNA Stability--drug effects
RNA, Messenger--drug effects
Transcriptional Activation
Tumor Necrosis Factor-alpha--pharmacology