Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

Gratton, J P

Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1. [electronic resource] - The Journal of biological chemistry Jul 2000 - 22268-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M001644200 doi


Animals
Biological Transport
Calmodulin--metabolism
Cattle
Caveolin 1
Caveolins
Cells, Cultured
Endothelium, Vascular--metabolism
Enzyme Activation
HSP90 Heat-Shock Proteins--metabolism
Membrane Proteins--metabolism
Nitric Oxide Synthase--metabolism
Nitric Oxide Synthase Type III
Phosphorylation