Long-term effects of the endothelin(A) receptor antagonist LU 135252 and the angiotensin-converting enzyme inhibitor trandolapril on diabetic angiopathy and nephropathy in a chronic type I diabetes mellitus rat model.

Dhein, S

Long-term effects of the endothelin(A) receptor antagonist LU 135252 and the angiotensin-converting enzyme inhibitor trandolapril on diabetic angiopathy and nephropathy in a chronic type I diabetes mellitus rat model. [electronic resource] - The Journal of pharmacology and experimental therapeutics May 2000 - 351-9 p. digital

Publication Type: Journal Article

0022-3565


Angiotensin-Converting Enzyme Inhibitors--therapeutic use
Animals
Blood Glucose--metabolism
Blood Pressure--drug effects
Blood Vessels--pathology
Body Weight--drug effects
Diabetes Mellitus, Experimental--drug therapy
Diabetic Angiopathies--drug therapy
Diabetic Nephropathies--drug therapy
Endothelin Receptor Antagonists
Endothelium, Vascular--pathology
Erythrocytes--drug effects
Heart Rate--drug effects
Indoles--therapeutic use
Kidney Function Tests
Male
Muscle, Smooth, Vascular--pathology
Myocardium--pathology
Phenylpropionates--therapeutic use
Pyrimidines--therapeutic use
Rats
Rats, Wistar
Receptor, Endothelin A