Identification of the mechanism responsible for the increased fibrin specificity of TNK-tissue plasminogen activator relative to tissue plasminogen activator.

Stewart, R J

Identification of the mechanism responsible for the increased fibrin specificity of TNK-tissue plasminogen activator relative to tissue plasminogen activator. [electronic resource] - The Journal of biological chemistry Apr 2000 - 10112-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.275.14.10112 doi


Alanine
Amino Acid Substitution
Fibrin--metabolism
Genetic Variation
Glycosylation
Humans
Kinetics
Models, Molecular
Protein Structure, Secondary
Recombinant Proteins--metabolism
Substrate Specificity
Tissue Plasminogen Activator--chemistry