Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones.

Shih, H

Rational design, synthesis and structure-activity relationships of antitumor (E)-2-benzylidene-1-tetralones and (E)-2-benzylidene-1-indanones. [electronic resource] - Bioorganic & medicinal chemistry letters Mar 2000 - 487-90 p. digital

Publication Type: Journal Article

0960-894X

10.1016/s0960-894x(00)00032-9 doi


Antineoplastic Agents--chemical synthesis
Benzylidene Compounds--chemical synthesis
Drug Screening Assays, Antitumor
Humans
Jurkat Cells
Magnetic Resonance Spectroscopy
Molecular Conformation
Structure-Activity Relationship
Tetrazolium Salts
Thiazoles
Tumor Cells, Cultured