Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents.
Zisterer, D M
Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents. [electronic resource] - The Journal of pharmacology and experimental therapeutics Apr 2000 - 48-59 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
Animals
Apoptosis--drug effects
Blotting, Western
Caspase 3
Caspases--analysis
Cell Line
Cycloheximide--pharmacology
Cytochrome c Group--metabolism
Cytosol--drug effects
DNA Fragmentation--drug effects
Electrophoresis
Enzyme Precursors--analysis
HL-60 Cells
Humans
Jurkat Cells
Liver--cytology
NF-kappa B--genetics
Oxazepines--pharmacology
Oxidative Stress--physiology
Protein Synthesis Inhibitors--pharmacology
Pyrroles--pharmacology
Radioligand Assay
Rats
T-Lymphocytes--drug effects
Up-Regulation--drug effects
Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents. [electronic resource] - The Journal of pharmacology and experimental therapeutics Apr 2000 - 48-59 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
Animals
Apoptosis--drug effects
Blotting, Western
Caspase 3
Caspases--analysis
Cell Line
Cycloheximide--pharmacology
Cytochrome c Group--metabolism
Cytosol--drug effects
DNA Fragmentation--drug effects
Electrophoresis
Enzyme Precursors--analysis
HL-60 Cells
Humans
Jurkat Cells
Liver--cytology
NF-kappa B--genetics
Oxazepines--pharmacology
Oxidative Stress--physiology
Protein Synthesis Inhibitors--pharmacology
Pyrroles--pharmacology
Radioligand Assay
Rats
T-Lymphocytes--drug effects
Up-Regulation--drug effects