Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents.

Lamb, D C

Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents. [electronic resource] - Chemico-biological interactions Mar 2000 - 165-75 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-2797

10.1016/s0009-2797(99)00169-6 doi


Antifungal Agents--pharmacology
Azoles--pharmacology
Candida albicans--drug effects
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--metabolism
Humans
Isoenzymes--antagonists & inhibitors
Mixed Function Oxygenases--antagonists & inhibitors
Oxidoreductases--antagonists & inhibitors
Species Specificity
Sterol 14-Demethylase
Substrate Specificity