The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity.

Beamish, H J

The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity. [electronic resource] - Nucleic acids research Apr 2000 - 1506-13 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1362-4962

10.1093/nar/28.7.1506 doi


Animals
B-Lymphocytes--enzymology
Base Sequence
CHO Cells
Cell Line
Chromosomes, Artificial, Yeast--genetics
Conserved Sequence
Cricetinae
DNA Primers--genetics
DNA Repair--genetics
DNA-Activated Protein Kinase
DNA-Binding Proteins
Hematopoietic Stem Cells--enzymology
Mice
Mice, SCID
Mutagenesis, Site-Directed
Phosphatidylinositol 3-Kinases--chemistry
Protein Serine-Threonine Kinases--chemistry
Protein Structure, Tertiary