A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice.

Helgason, C D

A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice. [electronic resource] - The Journal of experimental medicine Mar 2000 - 781-94 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-1007

10.1084/jem.191.5.781 doi


Animals
Apoptosis
B-Lymphocytes--immunology
Bone Marrow Cells--immunology
Bone Marrow Transplantation
Cell Cycle
Ficoll--analogs & derivatives
Flow Cytometry
Immunity, Cellular
Immunoglobulin M
Lymph Nodes--cytology
Mice
Mice, Inbred NOD
Mice, Mutant Strains
Mice, SCID
Mitogen-Activated Protein Kinases--metabolism
Myeloproliferative Disorders
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
Phosphoric Monoester Hydrolases--immunology
Phosphorylation
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-akt
Receptors, Antigen, B-Cell
Signal Transduction
Spleen--cytology
Trinitrobenzenes--immunology
src Homology Domains--immunology