FGF-2 isoforms of 18 and 22.5 kDa differentially modulate t-PA and PAI-1 expressions on the pancreatic carcinoma cells AR4-2J: consequences on cell spreading and invasion.

Escaffit, F

FGF-2 isoforms of 18 and 22.5 kDa differentially modulate t-PA and PAI-1 expressions on the pancreatic carcinoma cells AR4-2J: consequences on cell spreading and invasion. [electronic resource] - International journal of cancer Feb 2000 - 555-62 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0020-7136

10.1002/(sici)1097-0215(20000215)85:4<555::aid-ijc18>3.0.co;2-h doi


Animals
Cell Division--drug effects
Collagen
Doxycycline--toxicity
Drug Combinations
Extracellular Matrix
Fibroblast Growth Factor 2--genetics
Gene Expression Regulation, Neoplastic--drug effects
Kinetics
Laminin
Mice
Mice, Nude
Molecular Weight
Mutagenesis, Site-Directed
Neoplasm Invasiveness
Neoplasm Metastasis
Pancreatic Neoplasms--genetics
Plasminogen Activator Inhibitor 1--genetics
Point Mutation
Protein Isoforms--genetics
Proteoglycans
Rats
Recombinant Proteins--metabolism
Tissue Plasminogen Activator--genetics
Transcription, Genetic
Transfection
Transplantation, Heterologous
Tumor Cells, Cultured
Urokinase-Type Plasminogen Activator--genetics