Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4.

Vandebriel, R J

Assessment of preferential T-helper 1 or T-helper 2 induction by low molecular weight compounds using the local lymph node assay in conjunction with RT-PCR and ELISA for interferon-gamma and interleukin-4. [electronic resource] - Toxicology and applied pharmacology Jan 2000 - 77-85 p. digital

Publication Type: Journal Article

0041-008X

10.1006/taap.1999.8841 doi


Allergens--pharmacology
Animals
Cells, Cultured
Dinitrochlorobenzene--immunology
Enzyme-Linked Immunosorbent Assay
Female
Interferon-gamma--biosynthesis
Interleukin-4--biosynthesis
Lymph Nodes--cytology
Lymphocyte Activation--drug effects
Male
Mice
Mice, Inbred BALB C
Molecular Weight
Phthalic Anhydrides--immunology
RNA, Messenger--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Th1 Cells--drug effects
Th2 Cells--drug effects
Toluene 2,4-Diisocyanate--immunology